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Genetic and Cellular Characterization of Caenorhabditis elegans Mutants Abnormal in the Regulation of Many Phase II Enzymes

BACKGROUND: The phase II detoxification enzymes execute a major protective role against xenobiotics as well as endogenous toxicants. To understand how xenobiotics regulate phase II enzyme expression, acrylamide was selected as a model xenobiotic chemical, as it induces a large number and a variety o...

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Detalhes bibliográficos
Main Authors: Hasegawa, Koichi, Miwa, Johji
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2887452/
https://ncbi.nlm.nih.gov/pubmed/20585349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011194
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