Long-Term Nicotine Adaptation in Caenorhabditis elegans Involves PKC-Dependent Changes in Nicotinic Receptor Abundance

Chronic exposure to nicotine leads to long-term changes in both the abundance and activity of nicotinic acetylcholine receptors, processes thought to contribute to nicotine addiction. We have found that in Caenorhabditis elegans, prolonged nicotine treatment results in a long-lasting decrease in the...

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Publicat a:J Neurosci
Autors principals: Waggoner, Laura E., Dickinson, Kari A., Poole, Daniel S., Tabuse, Yo, Miwa, Johji, Schafer, William R.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2000
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ARTICLE
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773091/
https://ncbi.nlm.nih.gov/pubmed/11102488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-23-08802.2000
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