Subcellular Localization of Wild-Type and Parkinson's Disease-Associated Mutant α-Synuclein in Human and Transgenic Mouse Brain

Mutations in the α-synuclein (αSYN) gene are associated with rare cases of familial Parkinson's disease, and αSYN is a major component of Lewy bodies and Lewy neurites. Here we have investigated the localization of wild-type and mutant [A30P]αSYN as well as βSYN at the cellular and subcellular...

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Vydáno v:J Neurosci
Hlavní autoři: Kahle, Philipp J., Neumann, Manuela, Ozmen, Laurence, Müller, Veronika, Jacobsen, Helmut, Schindzielorz, Alice, Okochi, Masayasu, Leimer, Uwe, van der Putten, Herman, Probst, Alphonse, Kremmer, Elisabeth, Kretzschmar, Hans A., Haass, Christian
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2000
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772969/
https://ncbi.nlm.nih.gov/pubmed/10964942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-17-06365.2000
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