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Suppressed Injury-Induced Rise in Spinal Prostaglandin E(2) Production and Reduced Early Thermal Hyperalgesia in iNOS-Deficient Mice
It is widely accepted that peripheral injury increases spinal inducible cyclooxygenase (COX-2) expression and prostaglandin E(2) (PGE(2)) formation as key mediators of nociceptive sensitization. Here, we used inducible nitric oxide synthase (iNOS) gene-deficient (iNOS−/−) mice to determine the contr...
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| 出版年: | J Neurosci |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Society for Neuroscience
2000
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6772960/ https://ncbi.nlm.nih.gov/pubmed/10964977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-17-06714.2000 |
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