Brain-Derived Neurotrophic Factor-Mediated Neuroprotection of Adult Rat Retinal Ganglion Cells In Vivo Does Not Exclusively Depend on Phosphatidyl-Inositol-3′-Kinase/Protein Kinase B Signaling

The neurotrophin brain-derived neurotrophic factor (BDNF) serves as a survival, mitogenic, and differentiation factor in both the developing and adult CNS and PNS. In an attempt to identify the molecular mechanisms underlying BDNF neuroprotection, we studied activation of two potentially neuroprotec...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Klöcker, Nikolaj, Kermer, Pawel, Weishaupt, Jochen H., Labes, Monika, Ankerhold, Richard, Bähr, Mathias
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772828/
https://ncbi.nlm.nih.gov/pubmed/10995840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-18-06962.2000
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