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Selective Regulation of N-Type Ca Channels by Different Combinations of G-Protein β/γ Subunits and RGS Proteins

We examined the effects of G-protein β and γ subunit heterodimers on human α(1B) (N-type) Ca channels expressed in HEK293 cells. All of the known β subunits (β1–β5) produced voltage-dependent inhibition of α(1B) Ca channels, depending on the γ subunit found in the heterodimer. β1–β4 subunits inhibit...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Zhou, Janice Y., Siderovski, David P., Miller, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772774/
https://ncbi.nlm.nih.gov/pubmed/11007869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-19-07143.2000
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