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The Evolution of Lipophilin Genes from Invertebrates to Tetrapods: DM-20 Cannot Replace Proteolipid Protein in CNS Myelin

The proteolipid protein (PLP) gene encodes two myelin-specific protein isoforms, DM-20 and PLP, which are members of the highly conserved lipophilin family of transmembrane proteins. While the functions of this family are poorly understood, the fact that null mutations of the PLP gene cause leukodys...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Stecca, Barbara, Southwood, Cherie M., Gragerov, Alexander, Kelley, Kevin A., Friedrich, Victor L., Gow, Alexander
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772626/
https://ncbi.nlm.nih.gov/pubmed/10818135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-11-04002.2000
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