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Disrupted Proteolipid Protein Trafficking Results in Oligodendrocyte Apoptosis in an Animal Model of Pelizaeus-Merzbacher Disease

Abstract. Pelizaeus-Merzbacher disease (PMD) is a dysmyelinating disease resulting from mutations, deletions, or duplications of the proteolipid protein (PLP) gene. Distinguishing features of PMD include pleiotropy and a range of disease severities among patients. Previously, we demonstrated that, w...

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Bibliografiset tiedot
Päätekijät: Gow, Alexander, Southwood, Cherie M., Lazzarini, Robert A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 1998
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2141744/
https://ncbi.nlm.nih.gov/pubmed/9472043
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