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Proteasome Involvement and Accumulation of Ubiquitinated Proteins in Cerebellar Granule Neurons Undergoing Apoptosis

We investigated the potential role of the ubiquitin proteolytic system in the death of cerebellar granule neurons induced by reduction of extracellular potassium. Inhibitors of proteasomal function block apoptosis if administered at onset of this process, but they do not exert such effect when added...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Canu, Nadia, Barbato, Christian, Ciotti, Maria Teresa, Serafino, Annalucia, Dus, Laura, Calissano, Pietro
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2000
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772397/
https://ncbi.nlm.nih.gov/pubmed/10632588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-02-00589.2000
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