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Proteasome Involvement and Accumulation of Ubiquitinated Proteins in Cerebellar Granule Neurons Undergoing Apoptosis

We investigated the potential role of the ubiquitin proteolytic system in the death of cerebellar granule neurons induced by reduction of extracellular potassium. Inhibitors of proteasomal function block apoptosis if administered at onset of this process, but they do not exert such effect when added...

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Detalles Bibliográficos
Publicado en:J Neurosci
Main Authors: Canu, Nadia, Barbato, Christian, Ciotti, Maria Teresa, Serafino, Annalucia, Dus, Laura, Calissano, Pietro
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772397/
https://ncbi.nlm.nih.gov/pubmed/10632588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-02-00589.2000
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