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Proteasome Involvement and Accumulation of Ubiquitinated Proteins in Cerebellar Granule Neurons Undergoing Apoptosis

We investigated the potential role of the ubiquitin proteolytic system in the death of cerebellar granule neurons induced by reduction of extracellular potassium. Inhibitors of proteasomal function block apoptosis if administered at onset of this process, but they do not exert such effect when added...

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Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Canu, Nadia, Barbato, Christian, Ciotti, Maria Teresa, Serafino, Annalucia, Dus, Laura, Calissano, Pietro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2000
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772397/
https://ncbi.nlm.nih.gov/pubmed/10632588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-02-00589.2000
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