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DNP‐Supported Solid‐State NMR Spectroscopy of Proteins Inside Mammalian Cells

Elucidating at atomic level how proteins interact and are chemically modified in cells represents a leading frontier in structural biology. We have developed a tailored solid‐state NMR spectroscopic approach that allows studying protein structure inside human cells at atomic level under high‐sensiti...

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Détails bibliographiques
Publié dans:Angew Chem Int Ed Engl
Auteurs principaux: Narasimhan, Siddarth, Scherpe, Stephan, Lucini Paioni, Alessandra, van der Zwan, Johan, Folkers, Gert E., Ovaa, Huib, Baldus, Marc
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772113/
https://ncbi.nlm.nih.gov/pubmed/31233270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201903246
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