DNP‐Supported Solid‐State NMR Spectroscopy of Proteins Inside Mammalian Cells

Elucidating at atomic level how proteins interact and are chemically modified in cells represents a leading frontier in structural biology. We have developed a tailored solid‐state NMR spectroscopic approach that allows studying protein structure inside human cells at atomic level under high‐sensiti...

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Detalles Bibliográficos
Publicado en:Angew Chem Int Ed Engl
Autores principales: Narasimhan, Siddarth, Scherpe, Stephan, Lucini Paioni, Alessandra, van der Zwan, Johan, Folkers, Gert E., Ovaa, Huib, Baldus, Marc
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
Materias:
Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772113/
https://ncbi.nlm.nih.gov/pubmed/31233270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201903246
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