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Hydrogen Bond Directed ortho‐Selective C−H Borylation of Secondary Aromatic Amides

Reported is an iridium catalyst for ortho‐selective C−H borylation of challenging secondary aromatic amide substrates, and the regioselectivity is controlled by hydrogen‐bond interactions. The BAIPy‐Ir catalyst forms three hydrogen bonds with the substrate during the crucial activation step, and all...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Bai, Shao‐Tao, Bheeter, Charles B., Reek, Joost N. H.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772079/
https://ncbi.nlm.nih.gov/pubmed/31237988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201907366
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