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A Mild Synthesis of Bicyclic Alkoxyoxazolium Salts from Proline and Pipecolic Acid Derivatives

A regio‐ and chemoselective preparation of bicyclic alkoxyoxazolium salts from amide derivatives of proline and pipecolic acid by electrophilic amide activation is reported. Mechanistic NMR experiments suggest an unusual role for the base and highlight the effect of substitution pattern of the subst...

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Detaylı Bibliyografya
Yayımlandı:European J Org Chem
Asıl Yazarlar: Spinozzi, Eleonora, Bauer, Adriano, Maulide, Nuno
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2019
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771909/
https://ncbi.nlm.nih.gov/pubmed/31598092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ejoc.201900985
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