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Direct Regioselective Synthesis of Tetrazolium Salts by Activation of Secondary Amides under Mild Conditions

[Image: see text] Tetrazolium salts are biologically active molecules that have found broad applications in biochemical assays. A regioselective synthesis of tetrazolium salts is described through a formal (3 + 2) cycloaddition. The possibility of employing simple amides and azides as starting mater...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Org Lett
Hauptverfasser: Tona, Veronica, Maryasin, Boris, de la Torre, Aurélien, Sprachmann, Josefine, González, Leticia, Maulide, Nuno
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2017
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5442602/
https://ncbi.nlm.nih.gov/pubmed/28485608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.7b01004
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