Activation of the Peroxisome Proliferator–Activated Receptor γ Coactivator 1β/NFATc1 Pathway in Circulating Osteoclast Precursors Associated With Bone Destruction in Rheumatoid Arthritis

OBJECTIVE: Activation of osteoclastogenesis at the bone site in rheumatoid arthritis (RA) is well established. The mechanisms by which circulating osteoclast precursors contribute are still unclear. Peroxisome proliferator–activated receptor γ coactivator 1β (PGC‐1β) is implicated in transcriptional...

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Gepubliceerd in:Arthritis Rheumatol
Hoofdauteurs: Ma, Jian‐Da, Jing, Jun, Wang, Jun‐Wei, Mo, Ying‐Qian, Li, Qian‐Hua, Lin, Jian‐Zi, Chen, Le‐Feng, Shao, Lan, Miossec, Pierre, Dai, Lie
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2019
Onderwerpen:
Rheumatoid Arthritis
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771785/
https://ncbi.nlm.nih.gov/pubmed/30802366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.40868
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