Transcriptional alterations in glioma result primarily from DNA methylation–independent mechanisms

In cancer cells, aberrant DNA methylation is commonly associated with transcriptional alterations, including silencing of tumor suppressor genes. However, multiple epigenetic mechanisms, including polycomb repressive marks, contribute to gene deregulation in cancer. To dissect the relative contribut...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Court, Franck, Le Boiteux, Elisa, Fogli, Anne, Müller-Barthélémy, Mélanie, Vaurs-Barrière, Catherine, Chautard, Emmanuel, Pereira, Bruno, Biau, Julian, Kemeny, Jean-Louis, Khalil, Toufic, Karayan-Tapon, Lucie, Verrelle, Pierre, Arnaud, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771409/
https://ncbi.nlm.nih.gov/pubmed/31533980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.249219.119
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