Transcriptional alterations in glioma result primarily from DNA methylation–independent mechanisms

In cancer cells, aberrant DNA methylation is commonly associated with transcriptional alterations, including silencing of tumor suppressor genes. However, multiple epigenetic mechanisms, including polycomb repressive marks, contribute to gene deregulation in cancer. To dissect the relative contribut...

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Bibliografski detalji
Izdano u:Genome Res
Glavni autori: Court, Franck, Le Boiteux, Elisa, Fogli, Anne, Müller-Barthélémy, Mélanie, Vaurs-Barrière, Catherine, Chautard, Emmanuel, Pereira, Bruno, Biau, Julian, Kemeny, Jean-Louis, Khalil, Toufic, Karayan-Tapon, Lucie, Verrelle, Pierre, Arnaud, Philippe
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2019
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771409/
https://ncbi.nlm.nih.gov/pubmed/31533980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.249219.119
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