Transcriptional alterations in glioma result primarily from DNA methylation–independent mechanisms

In cancer cells, aberrant DNA methylation is commonly associated with transcriptional alterations, including silencing of tumor suppressor genes. However, multiple epigenetic mechanisms, including polycomb repressive marks, contribute to gene deregulation in cancer. To dissect the relative contribut...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genome Res
Prif Awduron: Court, Franck, Le Boiteux, Elisa, Fogli, Anne, Müller-Barthélémy, Mélanie, Vaurs-Barrière, Catherine, Chautard, Emmanuel, Pereira, Bruno, Biau, Julian, Kemeny, Jean-Louis, Khalil, Toufic, Karayan-Tapon, Lucie, Verrelle, Pierre, Arnaud, Philippe
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2019
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6771409/
https://ncbi.nlm.nih.gov/pubmed/31533980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.249219.119
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