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Tumor Uptake of Triazine Dendrimers Decorated with Four, Sixteen, and Sixty-Four PSMA-Targeted Ligands: Passive versus Active Tumor Targeting

Various glutamate urea ligands have displayed high affinities to prostate specific membrane antigen (PSMA), which is highly overexpressed in prostate and other cancer sites. The multivalent versions of small PSMA-targeted molecules are known to be even more efficiently bound to the receptor. Here, w...

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Publicat a:Biomolecules
Autors principals: Lim, Jongdoo, Guan, Bing, Nham, Kien, Hao, Guiyang, Sun, Xiankai, Simanek, Eric E.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770530/
https://ncbi.nlm.nih.gov/pubmed/31466360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9090421
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