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Tumor Uptake of Triazine Dendrimers Decorated with Four, Sixteen, and Sixty-Four PSMA-Targeted Ligands: Passive versus Active Tumor Targeting

Various glutamate urea ligands have displayed high affinities to prostate specific membrane antigen (PSMA), which is highly overexpressed in prostate and other cancer sites. The multivalent versions of small PSMA-targeted molecules are known to be even more efficiently bound to the receptor. Here, w...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Lim, Jongdoo, Guan, Bing, Nham, Kien, Hao, Guiyang, Sun, Xiankai, Simanek, Eric E.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770530/
https://ncbi.nlm.nih.gov/pubmed/31466360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom9090421
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