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FGF23-Mediated Activation of Local RAAS Promotes Cardiac Hypertrophy and Fibrosis
Patients with chronic kidney disease (CKD) are prone to developing cardiac hypertrophy and fibrosis, which is associated with increased fibroblast growth factor 23 (FGF23) serum levels. Elevated circulating FGF23 was shown to induce left ventricular hypertrophy (LVH) via the calcineurin/NFAT pathway...
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| Опубликовано в: : | Int J Mol Sci |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
MDPI
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6770314/ https://ncbi.nlm.nih.gov/pubmed/31540546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20184634 |
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