Induction of cardiac FGF23/FGFR4 expression is associated with left ventricular hypertrophy in patients with chronic kidney disease

BACKGROUND: In chronic kidney disease (CKD), serum concentrations of fibroblast growth factor 23 (FGF23) increase progressively as glomerular filtration rate declines, while renal expression of the FGF23 coreceptor Klotho decreases. Elevated circulating FGF23 levels are strongly associated with mort...

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Detalhes bibliográficos
Publicado no:Nephrol Dial Transplant
Main Authors: Leifheit-Nestler, Maren, große Siemer, Robert, Flasbart, Kathrin, Richter, Beatrice, Kirchhoff, Felix, Ziegler, Wolfgang H., Klintschar, Michael, Becker, Jan U., Erbersdobler, Andreas, Aufricht, Christoph, Seeman, Tomas, Fischer, Dagmar-Christiane, Faul, Christian, Haffner, Dieter
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6388939/
https://ncbi.nlm.nih.gov/pubmed/26681731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ndt/gfv421
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