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FGF23-Mediated Activation of Local RAAS Promotes Cardiac Hypertrophy and Fibrosis
Patients with chronic kidney disease (CKD) are prone to developing cardiac hypertrophy and fibrosis, which is associated with increased fibroblast growth factor 23 (FGF23) serum levels. Elevated circulating FGF23 was shown to induce left ventricular hypertrophy (LVH) via the calcineurin/NFAT pathway...
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| Publié dans: | Int J Mol Sci |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
MDPI
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6770314/ https://ncbi.nlm.nih.gov/pubmed/31540546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20184634 |
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