Matched Whole-Genome Sequencing (WGS) and Whole-Exome Sequencing (WES) of Tumor Tissue with Circulating Tumor DNA (ctDNA) Analysis: Complementary Modalities in Clinical Practice

Tumor heterogeneity, especially intratumoral heterogeneity, is a primary reason for treatment failure. A single biopsy may not reflect the complete genomic architecture of the tumor needed to make therapeutic decisions. Circulating tumor DNA (ctDNA) is believed to overcome these limitations. We anal...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Imperial, Robin, Nazer, Marjan, Ahmed, Zaheer, Kam, Audrey E., Pluard, Timothy J., Bahaj, Waled, Levy, Mia, Kuzel, Timothy M., Hayden, Dana M., Pappas, Sam G., Subramanian, Janakiraman, Masood, Ashiq
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770276/
https://ncbi.nlm.nih.gov/pubmed/31546879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11091399
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