Matched Whole-Genome Sequencing (WGS) and Whole-Exome Sequencing (WES) of Tumor Tissue with Circulating Tumor DNA (ctDNA) Analysis: Complementary Modalities in Clinical Practice

Tumor heterogeneity, especially intratumoral heterogeneity, is a primary reason for treatment failure. A single biopsy may not reflect the complete genomic architecture of the tumor needed to make therapeutic decisions. Circulating tumor DNA (ctDNA) is believed to overcome these limitations. We anal...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Cancers (Basel)
Autori principali: Imperial, Robin, Nazer, Marjan, Ahmed, Zaheer, Kam, Audrey E., Pluard, Timothy J., Bahaj, Waled, Levy, Mia, Kuzel, Timothy M., Hayden, Dana M., Pappas, Sam G., Subramanian, Janakiraman, Masood, Ashiq
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770276/
https://ncbi.nlm.nih.gov/pubmed/31546879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11091399
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi