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Cyclosporin A Increases Mitochondrial Buffering of Calcium: An Additional Mechanism in Delaying Mitochondrial Permeability Transition Pore Opening
Regulation of mitochondrial free Ca(2+) is critically important for cellular homeostasis. An increase in mitochondrial matrix free Ca(2+) concentration ([Ca(2+)](m)) predisposes mitochondria to opening of the permeability transition pore (mPTP). Opening of the pore can be delayed by cyclosporin A (C...
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| Publicado no: | Cells |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6770067/ https://ncbi.nlm.nih.gov/pubmed/31500337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8091052 |
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