The Autocrine FGF/FGFR System in both Skin and Uveal Melanoma: FGF Trapping as a Possible Therapeutic Approach

Fibroblast growth factors (FGFs) play non-redundant autocrine/paracrine functions in various human cancers. The Cancer Genome Atlas (TCGA) data mining indicates that high levels of FGF and/or FGF receptor (FGFR) expression are associated with reduced overall survival, chromosome 3 monosomy and BAP1...

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Rezzola, Sara, Ronca, Roberto, Loda, Alessandra, Nawaz, Mohd Imtiaz, Tobia, Chiara, Paganini, Giuseppe, Maccarinelli, Federica, Giacomini, Arianna, Semeraro, Francesco, Mor, Marco, Presta, Marco
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770058/
https://ncbi.nlm.nih.gov/pubmed/31487962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11091305
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