Long Pentraxin 3-Mediated Fibroblast Growth Factor Trapping Impairs Fibrosarcoma Growth

Fibrosarcomas are soft tissue mesenchymal tumors originating from transformed fibroblasts. Fibroblast growth factor-2 (FGF2) and its tyrosine-kinase receptors (FGFRs) play pivotal roles in fibrosarcoma onset and progression, FGF2 being actively produced by fibroblasts in all stages along their malig...

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Библиографические подробности
Опубликовано в: :Front Oncol
Главные авторы: Rodrigues, Priscila Fabiana, Matarazzo, Sara, Maccarinelli, Federica, Foglio, Eleonora, Giacomini, Arianna, Silva Nunes, João Paulo, Presta, Marco, Dias, Adriana Abalen Martins, Ronca, Roberto
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2018
Предметы:
Oncology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6221954/
https://ncbi.nlm.nih.gov/pubmed/30443492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2018.00472
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