New Rat Model of Advanced NASH Mimicking Pathophysiological Features and Transcriptomic Signature of The Human Disease

Non-alcoholic steatohepatitis (NASH) is a major cause of chronic liver disease. However, most available animal models fail to reflect the whole spectrum of the disease. Liver fibrosis and portal hypertension are the strongest prognostic markers in advanced NASH. We herein aimed at developing a new m...

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Veröffentlicht in:Cells
Hauptverfasser: Maeso-Díaz, Raquel, Boyer-Diaz, Zoe, Lozano, Juan José, Ortega-Ribera, Martí, Peralta, Carmen, Bosch, Jaime, Gracia-Sancho, Jordi
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770035/
https://ncbi.nlm.nih.gov/pubmed/31510105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8091062
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