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New Rat Model of Advanced NASH Mimicking Pathophysiological Features and Transcriptomic Signature of The Human Disease

Non-alcoholic steatohepatitis (NASH) is a major cause of chronic liver disease. However, most available animal models fail to reflect the whole spectrum of the disease. Liver fibrosis and portal hypertension are the strongest prognostic markers in advanced NASH. We herein aimed at developing a new m...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Maeso-Díaz, Raquel, Boyer-Diaz, Zoe, Lozano, Juan José, Ortega-Ribera, Martí, Peralta, Carmen, Bosch, Jaime, Gracia-Sancho, Jordi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770035/
https://ncbi.nlm.nih.gov/pubmed/31510105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8091062
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