Emricasan Ameliorates Portal Hypertension and Liver Fibrosis in Cirrhotic Rats Through a Hepatocyte‐Mediated Paracrine Mechanism

In cirrhosis, liver microvascular dysfunction is a key factor increasing hepatic vascular resistance to portal blood flow, which leads to portal hypertension. De‐regulated inflammatory and pro‐apoptotic processes due to chronic injury play important roles in the dysfunction of liver sinusoidal cells...

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Enregistré dans:
Détails bibliographiques
Publié dans:Hepatol Commun
Auteurs principaux: Gracia‐Sancho, Jordi, Manicardi, Nicolò, Ortega‐Ribera, Martí, Maeso‐Díaz, Raquel, Guixé‐Muntet, Sergi, Fernández‐Iglesias, Anabel, Hide, Diana, García‐Calderó, Héctor, Boyer‐Díaz, Zoe, Contreras, Patricia C., Spada, Alfred, Bosch, Jaime
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2019
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601324/
https://ncbi.nlm.nih.gov/pubmed/31304452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1360
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