Emricasan Ameliorates Portal Hypertension and Liver Fibrosis in Cirrhotic Rats Through a Hepatocyte‐Mediated Paracrine Mechanism

In cirrhosis, liver microvascular dysfunction is a key factor increasing hepatic vascular resistance to portal blood flow, which leads to portal hypertension. De‐regulated inflammatory and pro‐apoptotic processes due to chronic injury play important roles in the dysfunction of liver sinusoidal cells...

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Detalhes bibliográficos
Publicado no:Hepatol Commun
Main Authors: Gracia‐Sancho, Jordi, Manicardi, Nicolò, Ortega‐Ribera, Martí, Maeso‐Díaz, Raquel, Guixé‐Muntet, Sergi, Fernández‐Iglesias, Anabel, Hide, Diana, García‐Calderó, Héctor, Boyer‐Díaz, Zoe, Contreras, Patricia C., Spada, Alfred, Bosch, Jaime
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6601324/
https://ncbi.nlm.nih.gov/pubmed/31304452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1360
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