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Effects of warm ischemia and reperfusion on the liver microcirculatory phenotype of rats: underlying mechanisms and pharmacological therapy

Warm ischemia and reperfusion (WIR) causes hepatic damage and may lead to liver failure, however the mechanisms involved are largely unknown. Here we have characterized the microcirculatory status and endothelial phenotype of livers undergoing WIR, and evaluated the use of simvastatin in WIR injury...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Hide, Diana, Ortega-Ribera, Martí, Garcia-Pagan, Juan-Carlos, Peralta, Carmen, Bosch, Jaime, Gracia-Sancho, Jordi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764954/
https://ncbi.nlm.nih.gov/pubmed/26905693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22107
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