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Effects of warm ischemia and reperfusion on the liver microcirculatory phenotype of rats: underlying mechanisms and pharmacological therapy

Warm ischemia and reperfusion (WIR) causes hepatic damage and may lead to liver failure, however the mechanisms involved are largely unknown. Here we have characterized the microcirculatory status and endothelial phenotype of livers undergoing WIR, and evaluated the use of simvastatin in WIR injury...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Hide, Diana, Ortega-Ribera, Martí, Garcia-Pagan, Juan-Carlos, Peralta, Carmen, Bosch, Jaime, Gracia-Sancho, Jordi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764954/
https://ncbi.nlm.nih.gov/pubmed/26905693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22107
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