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Purine-Metabolising Enzymes and Apoptosis in Cancer

The enzymes of both de novo and salvage pathways for purine nucleotide synthesis are regulated to meet the demand of nucleic acid precursors during proliferation. Among them, the salvage pathway enzymes seem to play the key role in replenishing the purine pool in dividing and tumour cells that requi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Camici, Marcella, Garcia-Gil, Mercedes, Pesi, Rossana, Allegrini, Simone, Tozzi, Maria Grazia
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769685/
https://ncbi.nlm.nih.gov/pubmed/31547393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11091354
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