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Purine-Metabolising Enzymes and Apoptosis in Cancer

The enzymes of both de novo and salvage pathways for purine nucleotide synthesis are regulated to meet the demand of nucleic acid precursors during proliferation. Among them, the salvage pathway enzymes seem to play the key role in replenishing the purine pool in dividing and tumour cells that requi...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Camici, Marcella, Garcia-Gil, Mercedes, Pesi, Rossana, Allegrini, Simone, Tozzi, Maria Grazia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769685/
https://ncbi.nlm.nih.gov/pubmed/31547393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11091354
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