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Purine-Metabolising Enzymes and Apoptosis in Cancer

The enzymes of both de novo and salvage pathways for purine nucleotide synthesis are regulated to meet the demand of nucleic acid precursors during proliferation. Among them, the salvage pathway enzymes seem to play the key role in replenishing the purine pool in dividing and tumour cells that requi...

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Détails bibliographiques
Publié dans:Cancers (Basel)
Auteurs principaux: Camici, Marcella, Garcia-Gil, Mercedes, Pesi, Rossana, Allegrini, Simone, Tozzi, Maria Grazia
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6769685/
https://ncbi.nlm.nih.gov/pubmed/31547393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11091354
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