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Differential Regulation of T Cell Immunity and Tolerance by Stromal Laminin Expressed in the Lymph Node
BACKGROUND: Stromal laminins α4 and α5 are differentially regulated in transplant tolerance and immunity, respectively, resulting in altered T cell trafficking. We hypothesized laminins directly regulated T cell activation and polarization. METHODS: Human and mouse CD4 T cells were activated in Th1,...
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| Publicado en: | Transplantation |
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| Autores principales: | , , , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6768765/ https://ncbi.nlm.nih.gov/pubmed/31343575 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TP.0000000000002774 |
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