The lymph node stromal laminin α5 shapes alloimmunity

Lymph node stromal cells (LNSCs) regulate immunity through constructing lymphocyte niches. LNSC-produced laminin α5 (Lama5) regulates CD4(+) T cells but the underlying mechanisms of its functions are poorly understood. Here we show that depleting Lama5 in LNSCs resulted in decreased Lama5 protein in...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Li, Lushen, Shirkey, Marina W., Zhang, Tianshu, Xiong, Yanbao, Piao, Wenji, Saxena, Vikas, Paluskievicz, Christina, Lee, Young, Toney, Nicholas, Cerel, Benjamin M., Li, Qinshan, Simon, Thomas, Smith, Kyle D., Hippen, Keli L., Blazar, Bruce R., Abdi, Reza, Bromberg, Jonathan S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2020
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7190966/
https://ncbi.nlm.nih.gov/pubmed/32017712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI135099
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi