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Neurofilaments in Pre-Symptomatic ALS and the Impact of Genotype

OBJECTIVE: To evaluate serum and cerebrospinal fluid (CSF) levels of phosphorylated neurofilament heavy (pNfH), and to compare these to levels of neurofilament light (NfL), as biomarkers of pre-symptomatic ALS. DESIGN: The study population includes 34 controls, 79 individuals at-risk for ALS, 22 ALS...

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Dades bibliogràfiques
Publicat a:Amyotroph Lateral Scler Frontotemporal Degener
Autors principals: Benatar, Michael, Wuu, Joanne, Lombardi, Vittoria, Jeromin, Andreas, Bowser, Robert, Andersen, Peter M, Malaspina, Andrea
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768722/
https://ncbi.nlm.nih.gov/pubmed/31432691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21678421.2019.1646769
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