A ubiquitin-like domain controls protein kinase D dimerization and activation by trans-autophosphorylation

Protein kinase D (PKD) is an essential Ser/Thr kinase in animals and controls a variety of diverse cellular functions, including vesicle trafficking and mitogenesis. PKD is activated by recruitment to membranes containing the lipid second messenger diacylglycerol (DAG) and subsequent phosphorylation...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Elsner, Daniel J., Siess, Katharina M., Gossenreiter, Thomas, Hartl, Markus, Leonard, Thomas A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2019
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768651/
https://ncbi.nlm.nih.gov/pubmed/31406020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008713
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