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Regulation of Yersinia Protein Kinase A (YpkA) Kinase Activity by Multisite Autophosphorylation and Identification of an N-terminal Substrate-binding Domain in YpkA

The serine/threonine protein kinase YpkA is an essential virulence factor produced by pathogenic Yersinia species. YpkA is delivered into host mammalian cells via a type III secretion system and localizes to the inner side of the plasma membrane. We have previously shown that YpkA binds to and phosp...

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Detalhes bibliográficos
Main Authors: Pha, Khavong, Wright, Matthew E., Barr, Tasha M., Eigenheer, Richard A., Navarro, Lorena
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4176208/
https://ncbi.nlm.nih.gov/pubmed/25086045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.601153
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