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Functional characterization of Aspergillus nidulans ypkA, a homologue of the mammalian kinase SGK.

The serum- and glucocorticoid-regulated protein kinase (SGK) is an AGC kinase involved in signal cascades regulated by glucocorticoid hormones and serum in mammals. The Saccharomyces cerevisiae ypk1 and ypk2 genes were identified as SGK homologues and Ypk1 was shown to regulate the balance of sphing...

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Autori principali: Ana Cristina Colabardini, Neil Andrew Brown, Marcela Savoldi, Maria Helena S Goldman, Gustavo Henrique Goldman
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2013-01-01
Serie:PLoS ONE
Accesso online:http://europepmc.org/articles/PMC3589345?pdf=render
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