A chromatin-based mechanism controls differential regulation of the cytochrome P450 gene Cyp24a1 in renal and non-renal tissues

Cytochrome P450 family 27 subfamily B member 1 (CYP27B1) and CYP24A1 function to maintain physiological levels of 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) in the kidney. Renal Cyp27b1 and Cyp24a1 expression levels are transcriptionally regulated in a highly reciprocal manner by parathyroid hormo...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Meyer, Mark B., Lee, Seong Min, Carlson, Alex H., Benkusky, Nancy A., Kaufmann, Martin, Jones, Glenville, Pike, J. Wesley
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768633/
https://ncbi.nlm.nih.gov/pubmed/31439663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010173
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