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Lack of Therapeutic Efficacy of an Anti-α(4)β(7) Antibody in SIVmac251-Infected Rhesus Macaques

Sustained virologic control of human immunodeficiency virus type 1 (HIV-1) infection following discontinuation of antiretroviral therapy (ART) is a major goal of the HIV-1 cure field. A recent study reported that anti-α(4)β(7) antibody administration induced durable virologic control following ART d...

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Vydáno v:Science
Hlavní autoři: Abbink, Peter, Mercado, Noe B., Nkolola, Joseph P., Peterson, Rebecca L., Tuyishime, Hubert, McMahan, Katherine, Moseley, Edward T., Borducchi, Erica N., Chandrashekar, Abishek, Bondzie, Esther A., Agarwal, Arshi, Belli, Aaron J., Reimann, Keith A., Keele, Brandon F., Geleziunas, Romas, Lewis, Mark G., Barouch, Dan H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768629/
https://ncbi.nlm.nih.gov/pubmed/31488689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaw8562
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