Prevention of SIVmac251 reservoir seeding in rhesus monkeys by early antiretroviral therapy

The precise time when the viral reservoir is seeded during acute HIV-1 infection remains unclear. We previously demonstrated that the viral reservoir was seeded by day 3 following SIVmac251 infection in rhesus monkeys. Here we report the impact of initiating ART on day 0 (6 h), 1, 2, or 3 following...

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Publicado en:Nat Commun
Main Authors: Whitney, James B., Lim, So-Yon, Osuna, Christa E., Kublin, Jessica L., Chen, Elsa, Yoon, Gyeol, Liu, Po-Ting, Abbink, Peter, Borducci, Erica N., Hill, Alison, Lewis, Mark G., Geleziunas, Romas, Robb, Merlin L., Michael, Nelson L., Barouch, Dan H.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6303321/
https://ncbi.nlm.nih.gov/pubmed/30575753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07881-9
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