Breast cancer-released exosomes trigger cancer-associated cachexia to promote tumor progression

Cancer-secreted exosomes are emerging mediators of cancer-associated cachexia. Here, we show that miR-155 secreted by breast cancer cells is a potent role on the catabolism of adipocytes and muscle cells through targeting the PPARγ. After cocultivated with mature adipocytes or C2C12, tumour cells ex...

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Publicado en:Adipocyte
Autores principales: Wu, Qi, Sun, Si, Li, Zhiyu, Yang, Qian, Li, Bei, Zhu, Shan, Wang, Lijun, Wu, Juan, Yuan, Jingping, Wang, Changhua, Li, Juanjuan, Sun, Shengrong
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2018
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768245/
https://ncbi.nlm.nih.gov/pubmed/30474469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21623945.2018.1551688
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