Exosomes from the tumour-adipocyte interplay stimulate beige/brown differentiation and reprogram metabolism in stromal adipocytes to promote tumour progression

BACKGROUND: Emerging evidence supports the pivotal roles of adipocytes in breast cancer progression. Tumour induced beige/brown adipose tissue differentiation contributes to the hypermetabolic state of the breast cancer. However, the mediators and mechanisms remain unclear. METHODS: Survival probabi...

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Foilsithe in:J Exp Clin Cancer Res
Main Authors: Wu, Qi, Li, Juanjuan, Li, Zhiyu, Sun, Si, Zhu, Shan, Wang, Lijun, Wu, Juan, Yuan, Jingping, Zhang, Yimin, Sun, Shengrong, Wang, Changhua
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2019
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6537177/
https://ncbi.nlm.nih.gov/pubmed/31138258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1210-3
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