Tumour-originated exosomal miR-155 triggers cancer-associated cachexia to promote tumour progression

Abstract Emerging evidence supports the pivotal roles of cancer-associated cachexia in breast cancer progression. However, the mediators and mechanisms that mediate cancer-induced cachexia remain unclear. Here, we show that breast cancer-derived exosomes alter adipocytes and muscle cells in terms of...

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Detalhes bibliográficos
Main Authors: Qi Wu, Si Sun, Zhiyu Li, Qian Yang, Bei Li, Shan Zhu, Lijun Wang, Juan Wu, Jingping Yuan, Changhua Yang, Juanjuan Li, Shengrong Sun
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2018-10-01
Colecção:Molecular Cancer
Assuntos:
Breast cancer
Exosomes
Cachexia
Tumour progression
Acesso em linha:http://link.springer.com/article/10.1186/s12943-018-0899-5
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