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Absence of the Lectin Activation Pathway of Complement Ameliorates Proteinuria-Induced Renal Injury

Proteinuria is an adverse prognostic feature in renal diseases. In proteinuric nephropathies, filtered proteins exert an injurious effect on the renal tubulointerstitium, resulting in inflammation and fibrosis. In the present study, we assessed to what extent complement activation via the lectin pat...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Alghadban, Samy, Kenawy, Hany I., Dudler, Thomas, Schwaeble, Wilhelm J., Brunskill, Nigel J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6768126/
https://ncbi.nlm.nih.gov/pubmed/31608060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02238
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