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Development of a practical synthesis of etravirine via a microwave-promoted amination
BACKGROUND: Etravirine (ETV) was approved as the second generation drug for use in individuals infected with HIV-1 in 2008 by the U.S. FDA with its unique antiviral activity, high specificity, and low toxicity. However, there are some shortcomings of the existing synthetic routes, such as the long r...
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| Publicado no: | Chem Cent J |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer International Publishing
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6768033/ https://ncbi.nlm.nih.gov/pubmed/30569261 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-018-0504-4 |
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