MAPK pathway activity plays a key role in PD‐L1 expression of lung adenocarcinoma cells

Immune checkpoint inhibitors targeting programmed cell death protein 1 (PD‐1) and programmed death‐ligand 1 (PD‐L1) have improved the survival of patients with non‐small cell lung cancer (NSCLC). Still, many patients do not respond to these inhibitors. PD‐L1 (CD274) expression, one of the factors th...

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Bibliografiske detaljer
Udgivet i:J Pathol
Main Authors: Stutvoet, Thijs S, Kol, Arjan, de Vries, Elisabeth GE, de Bruyn, Marco, Fehrmann, Rudolf SN, Terwisscha van Scheltinga, Anton GT, de Jong, Steven
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2019
Fag:
Original Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6767771/
https://ncbi.nlm.nih.gov/pubmed/30972766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.5280
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