The Effect of a High‐Fat Meal on the Pharmacokinetics of Brigatinib, an Oral Anaplastic Lymphoma Kinase Inhibitor, in Healthy Volunteers

Brigatinib, a next‐generation anaplastic lymphoma kinase (ALK) inhibitor, received accelerated approval in the United States for the treatment of patients with metastatic ALK(+) non–small‐cell lung cancer who have progressed on or are intolerant to crizotinib. A clinical study was conducted to asses...

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Bibliographic Details
Published in:Clin Pharmacol Drug Dev
Main Authors: Tugnait, Meera, Gupta, Neeraj, Hanley, Michael J., Venkatakrishnan, Karthik, Sonnichsen, Daryl, Kerstein, David, Dorer, David J., Narasimhan, Narayana
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6767012/
https://ncbi.nlm.nih.gov/pubmed/30570839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.641
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